What does it means, when 2-direction perturbed pathways are identified in the gage enrichment analysis?

Question

[Assa Yeroslaviz]

The gage method for enrichment analysis using ENTREZ Ids emphasizes on its capability to test for changes not only for up- and down-regulated pathways, but also for those with a 2-directional change.

I don't understand what this means biologically. Does it mean that the pathway is being significantly deregulated in both directions simultaneously, or that it contains genes that that show a deregulation in both directions?

thanks