VCF annotation with gnomADv4 using R package

Question

[DKA]

Hello, I was wondering if there is an R package that can assist in annotating a VCF file with gnomADv4 data. I would be grateful if you could provide me with any relevant information or direction to resources that could be of assistance. Thank you.

[zx8754]

Use VEP:

• https://www.ensembl.org/info/docs/tools/vep/script/vep_example.html#gnomad

[DKA]

Sorry if this sounds naive but I am a newbie in R. Can I use VEP in R, please? Also, is it guaranteed that VEP will allow the annotation with gnomADv4? The link you are providing shows files for earlier releases. Thank you for your guideness.