Meta analysis of two GWAS summary statistics: one study is case-control and the other is quantitative
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7 months ago
Pine ▴ 20

I have two GWAS summary statistics for a trait that was evaluated differently in each study: one was evaluated as a case/control trait [Ex. diagnosis by a medical staff] and in another was measured as a quantitative trait [Ex. concentration of a blood marker for the trait]. Can these summary statistics be used together for a meta-analysis? And if so, I appreciate any advice or suggestions on how to go about it?

Thank you in advance!

GWAS Meta-analysis • 314 views
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