PDB related issue
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6 months ago
Nafi • 0

I am having trouble in the following pdb: 1M7D pdb link.

The problem is: in chain A, after residue id 27 there are 5 other residues having seq numbers: 27A, 27B, 27C, 27D, 27E. Then after that 28 resumes normally. What is the reason for this? Does it signify any special thing?

rcsb pdb • 392 views
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The best way to find out is to read the original paper. My guess is that the residue has been crystallized in alternative conformations, which are signified by those A-E letters..

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You can typically find much more useful info in the cif file, for example what you've found is called '_atom_site.pdbx_PDB_ins_code ' and described here; https://mmcif.wwpdb.org/dictionaries/mmcif_pdbx_v40.dic/Items/_atom_site.pdbx_PDB_ins_code.html

As Mensur Dlakic wrote, you'll need to read the paper for the context.

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