Cellosaurus release 49 is available on https://www.cellosaurus.org/
1) Statistics
- 153642 cell lines (113673 human, 27737 mouse, 2887 rat)
- 841 species represented
- 114358 synonyms
- 454841 cross-references to 110 resources (cell line catalogs, databases, ontologies, etc.)
- 160014 references to 27882 distinct publications (papers, patents, theses, etc.)
- 14370 web links
- 8855 human, mouse and dog cell lines with STR profiles (from 885 distinct sources)
- 2443 NCIt and 1351 ORDO (Orphanet) disease terms cited
- 834 UBERON and 260 CL terms cited
Since release 48 of January 2024:1415 entries were created and15091 entries were updated
2) Integration of plant cell lines
We introduced a small number (30) of plant cell lines at this release. These are the cell lines that have been (or are still) used by the community. Many other plant cell lines have been established but seem to never have been used. We do not plan to include them in the Cellosaurus.
The plant cell line entries have a new CC group line:
CC Group: Plant cell line.
3) Changes in the DR lines
3a) Cross-references were added to the cell lines entries from the Hysigen cell line collection.
Corresponding entry in the file cellosaurus_xrefs.txt:
Abbrev: Hysigen
Name : Hysigen cell line collection
Server: https://hysigen.com/
Db_URL: https://hysigen.com/%s.html
Term. : No
Cat : Cell line collections (Providers)
//
Example: DR Hysigen; CGKO-M2345
3b) Cross-references were added to the cell lines entries from the RIKEN BRC Experimental Plant Division (RIKEN_BRC_EPD).
Corresponding entry in the file cellosaurus_xrefs.txt:
Abbrev: RIKEN_BRC_EPD
Name : RIKEN BRC Experimental Plant Division cell lines
Server: https://epd.brc.riken.jp/en/
Db_URL: https://plant.rtc.riken.jp/resource/cell_line/cell_line_detail.html?brcno=%S
Term. : No
Cat : Cell line collections (Providers)
//
Example: DR RIKEN_BRC_EPD; rpc00001
4) Changes in the XML file
We made a number of important changes in the XML format file, these are accompanied by the corresponding changes in the XSD file.
- The elements <terminology-list>, <terminology> and <cv-term> are now obsolete.
- The <cv-term> elements are replaced with <xref> elements.
- The <xref> element has been modified: the <property-list> sub-element has been replaced with <label> and <discontinued> sub-elements.
- The <comment> element with category="Transfected with" now have an optional <xref> element instead of the previous <xref-list> element.
- In the elements <comment>, <doubling-time>, <genome-ancestry>, <hla-typing>, <microsatellite-instability>, <monoclonal-antibody-isotype>, <sequence-variation> and <str-list>, the source of the annotation, when available, now appears in a <source> element.
- When multiple sources are expected, <source> elements appear in a <source-list> element.
- As a consequence the elements <comment-sources>, <doubling-time-sources>, <genome-ancestry-source>, <hla-typing-source>, <microsatellite-instability-sources>, <monoclonal-antibody-isotype-sources>, <str-sources>, <variation-sources> are now obsolete.
- The <source> element can contain plain text and/or either a <xref> or a <reference> element.
