chIP-seq vs ATACseq analysis

Question

[QX]

Hi all,

I am trying to work on some ATACseq data analysis, however most of tutorials I found are on ChIPseq data analysis.

Is there any difference between the two analysis pipeline?

[Ming Tommy Tang]

This is my ATACseq processing pipeline https://github.com/crazyhottommy/pyflow-ATACseq depends on what you do, it has similar steps as ChIPseq as MolGeek said.

[QX]

Oh I actually looking at this pipeline, you are the author. Many thanks!

Answer 1

[MolGeek]

Depending on the question you are researching on. The analysis of ATAC Seq has similar steps with the Chip Seq analysis, but some adjustments might be needed. A good tutorial you can try is this one:

ATAC Seq