Example human WGS fastq data

Question

[ramiro.barrantes]

I am developing a human variant discovery pipeline and I need some whole genome sequence human data to test it. That is, I have found, not so easy to find. Ideally it would be tumor normal but perhaps any two different WGS human fastq data would suffice as I would run it, and eventually get some vcf files with variants that I can process. Any suggestions?

Answer 1

[bhumm]

I recommend you look around NCBI's Sequence Read Archive. You can browse for a variety of different sequencing data sets in a very granular manner (i.e., tissue type, paired normals, sequencing platform, etc.).

I have also found this Biostars post to be particularly helpful in downloading the data locally.

Answer 2

[Ming Tommy Tang]

Take a look at Genome in a Bottle https://www.nist.gov/programs-projects/genome-bottle