Cell fractions (from single cell) as variable in Cox Survival model
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5 months ago
Bine ▴ 90

Good afternoon,

I am wondering if anyone could advise me on the following:

I have obtained cell fractions (e.g. 0.2 endothelial cells, 0.6 epithelial cells and 0.2 T cells, total of 100%) and I would like to adjust my survival model with it.

Could I just add it to the model as shown below or should I somehow transform this metric?

My model:

model_cox<-coxph(Surv(PFI.t_5y, PFI.e_5y)~ gender + age  + cell_fraction_percentage, data = data, model=TRUE)

Thank you very much for any input!

Cox single-cell • 194 views
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