Forum:Good Bioinformatics Jokes/Puns?
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5 months ago
echolley ▴ 20

Does anybody have any good bioinformatics jokes/puns? I need to a few for a presentation and was wondering if anybody had any funny ones!

bioinformatics • 2.0k views
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5 months ago
Michael 55k

Gene Regulation:

Why did the gene go to therapy?

It couldn't express itself.

(GPT 4o)

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5 months ago

https://x.com/FedeBioinfo/status/1544623300051091457

In bioinformatics introduction lectures, I like to say that Excel came before Tinder... in seeing everything as a potential date

When you're starting with #bioinformatics, you will spend 3 hours writing a script for a task that could have been completed in 30 minutes with an appropriate existing tool. Later, you will spend 3 hours searching for a tool to avoid 30 minutes writing an appropriate script.

Real bioinformaticians don't read paper - Github README.md is surely enough

1 vs chr1 Slowing down #bioinformatics since 2003.

No, bioinformatics efficiency is defined by time faffing around installing dependencies.

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5 months ago

What's the difference between mapped bam and unmapped bam formats?

Unmapped is close to mapped, but no CIGAR.

What are the three most common causes for programming errors?

Bad variable names, and one-off errors.

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Sorry, I don't get it. Can you (or Captain Obvious) explain the jokes ? (non native english speaker here)

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"Close but no cigar" is a (primarily at least) British saying meaning you almost achieved something/completed something but didn't quite make it.

I don't know if I'm right on this, but I've always assumed the origin of this is because people will often smoke a cigar to celebrate a 'victory', so if you don't quite get there, you don't get your celebratory cigar.

I assume people are familiar with why CIGAR is a bioinfx pun

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AFAIK, cigars where prizes for fair games in the old days. Like the ones you're shooting stuff. Close, but no cigar would mean you hit some of the targets but you didn't get the prize.

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Why should you marry a bioinformatician? They know how to merge and commit.


Three programmers sit in a bar and start arguing about who works with the oldest code.

The first one says, "I use C! It's been around since more than 50 years!" The second one laughs and replies, "That's nothing. I code in COBOL, which dates back to 1959!" The third programmer smirks and says, "Oh please, I work with Fortran. My language is so old, it almost predates the computer!"

A bioinformatician sitting at the neighboring table, overhearing their dispute, looks up from his laptop, gives them a stern look and chimes in: "Gentlemen, can you please take your argument outside? I still have some DNA to analyze!"


A small group of machine-learning experts and another small group of computational biologists are taking the same train to a conference. Much to the surprise of the machine-learning experts, the computational biologists only bought a single ticket. When the conductor comes around, the computational biologists quickly squeeze into the bathroom and slide the ticket under the door. The machine-learning experts are impressed and decide to use the same trick on the return trip.

On the way back, the machine-learning experts are baffled to see that the computational biologists haven't bought any tickets at all. When the conductor enters the coach, the machine-learning experts quickly hide in the bathroom. One of the computational biologists follows them, knocks on the door, and says in a deep voice, "Ticket please!" As the machine-learning experts slide their ticket under the door, the computational biologists take it and head off to a second bathroom.

And the moral of the story? It never harms to truly understand the methods before applying them!

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5 months ago
Joe 21k

Not bioinformatics strictly per se but:

What do incels and Excel have in common?

Confusing things for a date.

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I remember the Venn version of this joke.

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5 months ago
Michael 55k

Not funny!

Not funny

Really not...

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He is not sorry.

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And he knew it.

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5 months ago
bk11 ★ 3.0k

Here are some bioinformatics jokes for you:

  1. Why was the cell's computer so frustrated? Because it had too many windows open!
  2. Why did the biologist go to the bar? To get a little culture.
  3. Why are biologists great at solving problems? They know how to find solutions at the molecular level!
  4. Why don't proteins tell jokes? Because they might unfold!
  5. Why did the bacterium fail the math test? It thought division and multiplication were the same thing.
  6. Why do bioinformaticians love coffee? Because they do all their best coding when they're caffeinated!
  7. Why did the DNA go to the party? Because it wanted to unwind!
  8. Why did the gene apply for a job? It wanted to express itself.
  9. Why do bioinformaticians prefer using Unix? Because they can't live without grep.
  10. What do you call a bacterial cell that is also a programmer? A nerd (since bacteria don't have a nucleus).
  11. Why did the bioinformatician get a job in construction? Because they excel at building pipelines.
  12. How does a bioinformatician hold a party? They sequence events!

I hope these bring a smile to your face!

(Source: GPT 4o)

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