4-way plot for comparing DEGs between 4 genotypes

Question

[jaint1]

Hello

I have sequencing data from mice of 4 genotypes, and i want to figure out a way to plot DEGs from gen1-vs-gen2 (x axis) and gen3-vs-gen4 (y axis) on a single plot. Do people have suggestions on how i can do this? I want this plot to replace a Venn diagram i currently have.

Thanks!

Answer 1

[dthorbur]

If I've understood correctly you can use an upset plot for that kind of comparison. Here is a link to an example using the R library UpSetR.