Job description
We are looking for a highly motivated, enthusiastic and creative PhD student in (epi)genetics, bioinformatics or related fields, to join the individual and forensic (epi)genomics research group led by Dr. Athina Vidaki, embedded within the Department of Clinical Genetics at Maastricht UMC+ and the Department of Genetics & Cell Biology at Maastricht University.
The successful applicant will contribute to our recently funded research by the Dutch Research Council (NWO, Vidi grant) to conduct innovative, technology-driven research in the areas of human individuality, the repetitive (epi)genome and long-read sequencing. Additionally, as part of a multidisciplinary environment with the core goal of innovating healthcare, you will also contribute to other ongoing projects in clinical (epi)genomics. You will be supervised and mentored by an experienced team within MUMC+ and UM, and exposed to a wide network of international collaborators.
In the UNIQUE research project, you will employ cutting-edge computational and experimental tools to produce and analyze whole-genome and targeted nanopore sequencing data. The ultimate goal is to uncover novel biomarkers of DNA uniqueness, applicable also to identical twins. For this purpose, you will develop, optimise and validate your own lab and programming techniques to analyze diverse types of repetitive DNA. You will also employ a wide range of methods in data analysis, statistics and prediction modelling, to study and infer a wide range of natural and disease-related phenotypes.
As a PhD student within the individual and forensic (epi)genomics group, you will also be trained to perform key researcher activities, including keeping up with current literature and analysis tools in the project area, developing and maintaining laboratory notes, easy-to-implement codes and results reporting (including contributing to preparation of official documents to NWO), collaborating with other team members including international colleagues, actively engaging in multidisciplinary meetings and research, contributing towards organizing events, and writing scientific publications.
Importantly, you will also get plenty of chances to develop your professional skills, including by presenting your research at conferences and connecting with societal stakeholders including companies and the general public. Finally, you will also get opportunities to build university educational experience, by supporting under/post-graduate students during their research projects, and contributing to teach activities of the group.
The anticipated start date is autumn 2024 (i.e. October 1st), but reasonable accommodations can be made for the right candidate.
Requirements
We are looking for a curious, pro-active and ambitious young researcher, with a successfully completed university MSc degree in (epi)genetics, molecular biology, biomedical sciences, bioinformatics, computational biology or related fields.
Key qualifications and skills:
- A strong quantitative and analytical mindset
- Excellent theoretical and experimental research skills
- Background and training in both wet- and dry-lab genetics instruments/methods; experience with epigenetics, nanopore sequencing and genome-wide techniques is a plus
- Sound knowledge in bioinformatics and biostatistics; basic programming skills in Python and/or R (and other languages) is a must
- Capacity to quickly acquire new knowledge and master new skills
- Strong problem-solving skills and ability to develop innovative ideas in a research project; experience in technology development is an asset
- Detail-oriented and result-driven attitude
- Ability to work both independently and in a multidisciplinary team
- Excellent communication, teamwork and organization skills
- Proficient written and oral English language skills (working language of the group); knowledge of the Dutch language is not required but appreciated*
Curious?
Are you interested in this exciting position but still have questions? Feel free to contact Athina Vidaki at athina.vidaki@maastrichtuniversity.nl for more information.
Applying?
Or are you already convinced and ready to become our new PhD Candidate in the role of repetitive (epi)genome in shaping human individuality? Apply now, no later than July 26, 2024, for this position, using this link.
Please upload your CV and motivation letter.
Information about the university, faculty and department, as well as employment conditions and benefits can be found on the official vacancy link.
