News:New more compact NCBI BLAST Core Nucleotide Database (core_nt) now available on the web
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PeterC_NCBI ▴ 510

NCBI now offers the core nucleotide database (core_nt), an alternative to the default nt database that contains better-defined content and is less than half the size of nt.

Benefits of BLAST core_nt over nt

  • Enables faster searches
  • Returns similar top results for most searches
  • Reduces redundancy for some highly represented organisms
  • Allows easier download and requires less storage space for database download for standalone BLAST (downloads available in August)

Note: core_nt will become the default nucleotide database in August 2024.

See our NCBI Insights post for more details and Try it out!

NCBI BLAST • 1.2k views
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When will this core_nt database be available for download

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It is available for download now: https://ftp.ncbi.nih.gov/blast/db/

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