Somatic Variant Calling from Nanopore Data

Question

[adarsh_munna]

Hi,

I have some cancer samples and normal control samples, sequenced by Nanopore (Amplicon sequencing). I read about ClairS from one source. I am just curious to know if there are any more tools for doing similar work.

Please suggest.

Thanks

Answer 1

[giulia.trauzzi]

Hi, I am not an expert but have you looked at the software EPI2ME from Nanopore for variant calling?

[GenoMax]

For reference https://github.com/epi2me-labs/wf-human-variation