Setting up a case control with 18 VCFs in plink?
0
0
Entering edit mode
10 weeks ago
atopasn1 • 0

Hello, I have 18 VCFs, and I want to use plink to do a case-control study to look for a series of SNPs that may be causing the phenotype I'm seeing. I've got two questions:

  1. How would the set-up go? I imagine I would need to merge all of my VCFs into one using bcftools and then convert them into a .map file. Is this correct?

  2. I am creating the .ped file from scratch. I do not have any information on the SNPs I want to investigate, as the reference genome for this organism is fairly new. The information on the website for plink is not clear, can I proceed with a .ped file that only has individual IDs and a phenotype?

Thanks!

case-control plink WGS • 199 views
ADD COMMENT

Login before adding your answer.

Traffic: 1958 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6