Changing Cellchat labels or group.by function

Question

[odi]

Hey everyone, I am new to using cellchat. I noticed looking at the steps using their github page, that to create a cellchat object, one has to identify what groups they would like to infer communication between. So example, according to the tutorial,

createCellChat(object = sce, group.by = "sce.clusters")

Meaning they will be identifying cell-cell communication between the sce.clusters. In my case, i want to identify cell-cell communication for the cell type + oxygen group; so, Bcell + Hypoxia. If i create that combination as a new metadata, i am interested in knowing if it actually reflects in the cell-cell communication or its only changes my "group.by".