ClusterProfiler GO / KEGG enrichment analysis for non Model organism

Question

[Pegasus]

Hi everyone,

I’ve been exploring discussions on using ClusterProfiler for non-model organisms, particularly non-pathogenic microbes, and thought it would be helpful to consolidate some useful resources for others who might have the same questions. Below are the key links (in addition to the main publications):

• KEGG Enrichment Analysis with Latest Online Data Using ClusterProfiler
• Using ClusterProfiler as a Universal Enrichment Analysis Tool
• GitHub: Enrichment Analysis for Non-Model Organisms
• how-to-perform-kegg-and-go-enrichment-analysis-of-non-model-species-using-r

The main required input in such cases is a gene-to-KEGG ID mapping list.

It would be very helpful if anyone could share the full R script for KEGG enrichment analysis using ClusterProfiler, assuming the user already has the list of gene-to-KEGG IDs available.

Looking forward to your insights and any shared scripts!

Cheers,