Entering edit mode
13 days ago
georgii.vdovin
•
0
Hello, I am trying to implement a ssGSEA for a conserved list of genes. I want to be able to calculate an enrichment score that is comparable between 2 species (mouse and axolotl); comparing activity of a given pathway. If I run the analysis only on genes that have one-to-one orthologous mappings, would it be possible to obtain comparable metrics? I am running it on log-transformed kallisto-derived TPM.