Alignment algorithm for DNA sequencing

Question

[QX]

Hi all,

I am working on some alignment of DNA sequencing, < 150 bp. are there some common library/algorithm that I can use for this alignment problem? ether python or R

and what will be the difference with the global search like bwa-mem or bowtie?

[ATpoint]

some alignment of DNA sequencing

This is not an adequate description of what you achieve to do. Please say why common tools, such as the ones you mention do not suffice, what what desired tool should do differently.

[GenoMax]

You can use bbmap with the local=t option if you need local alignments. bowtie v.1.x does ungapped alignments.