Error using DWLS

Question

[Ana]

Hi! I am trying to create the signature matrix from the single-cell reference using buildSignatureMatrixMAST to then run solveDampenedWLS. The function seems to run fine, and the intermediate files are created, but at some point I get this error:

Error in h(simpleError(msg, call)) :  error in evaluating the argument 'x' in selecting a method for function 'as.data.frame': incorrect number of dimensions Called from: h(simpleError(msg, call))

Any idea of why that can be happening or if there is a way to get around it to continue with the pipeline? Thanks.