Use Seed or Full Alignments from Pfam HMM as a filter step
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10 days ago
Janelyn123 • 0

Apologies for the very stupid question as I am starting out in this field. I am working with short read metagenomic sequences. I was wondering if I can use seed or full alignments from Pfam hmm models to filter metagenomic reads through alignment before feeding it to hmmscan. My intention is to reduce overall run time. In this context, I am trying to only retrieve reads with recombinase in them.

hmm sequences metagenomic • 221 views
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