Identify enzymes among a list of Uniprot ACs

Question

[miquelduranfrigola]

Hi all,

I have a list of human Uniprot ACs and I would like to identify all enzymes among them. How would you do this?

Thanks,

Miquel

Answer 1

[David Westergaard]

Well, I guess a simple, and not so sophisticated approach, would be to download either the txt file (e.g. http://www.uniprot.org/uniprot/O14733.txt ) or the xml file (e.g. http://www.uniprot.org/uniprot/O14733.xml ) and extract the EC number. This is assuming an EC number has been assigned to all enzymes (I'm not quite sure about this part, to be honest.)

Answer 2

[cdsouthan]

Upload the IDs to the UniProt ID mapper (e.g. as UniProt-to-UniProt) then simply select EC number on the display option

[hpmcwill]

The UniProt ID Mapping service can be found at: http://www.uniprot.org/mapping/

Documentation for the service is at http://www.uniprot.org/help/mapping/

Details of how to use the UniProt RESTful Web Services to automate requests to the ID Mapping service can be found at: http://www.uniprot.org/faq/28

[cdsouthan]

Hamish, for giving you the perfect lead-in, thats a beer next time I'm over. But, when is the inteface going to store query history (a la Entrez) to make the Booleans easier?