0
votes
3
replies
76
views
1
vote
0
replies
91
views
835
votes
169
replies
172k
views
110 follow
updated 6 months ago by
Biostar
3.4k
•
written 8.3 years ago by
Istvan Albert
102k
0
votes
0
replies
71
views
0
votes
3
replies
432
views
updated 8 hours ago by
GenoMax
150k
•
written 1 day ago by
Wu-Sheng Zhang
•
0
0
votes
2
replies
162
views
0
votes
0
replies
98
views
updated 1 day ago by
Pierre Lindenbaum
165k
•
written 1 day ago by
swarnadurga66666m
•
0
0
votes
1
reply
123
views
updated 1 day ago by
GenoMax
150k
•
written 1 day ago by
Yongjie Zhang
▴
110
0
votes
1
reply
127
views
updated 1 day ago by
Mensur Dlakic
★
29k
•
written 1 day ago by
Yongjie Zhang
▴
110
2
votes
3
replies
2.2k
views
updated 1 day ago by
Dan A
•
0
•
written 3.7 years ago by
Agenor Neto
▴
10
1
vote
1
reply
156
views
0
votes
0
replies
96
views
0
votes
2
replies
215
views
updated 2 days ago by
Istvan Albert
102k
•
written 2 days ago by
louis-gil
•
0
2
votes
1
reply
345
views
0
votes
1
reply
436
views
1
vote
2
replies
269
views
0
votes
3
replies
1.5k
views
updated 2 days ago by
Bastien Hervé
6.2k
•
written 22 months ago by
Sun
•
0
0
votes
0
replies
152
views
3 days ago by
csag6433
•
0
0
votes
2
replies
725
views
3
votes
4
replies
3.2k
views
8
votes
3
replies
302
views
1
vote
1
reply
188
views
updated 3 days ago by
Ram
45k
•
written 3 days ago by
reddyraghuveer664
•
0
0
votes
0
replies
148
views
0
votes
1
reply
189
views
updated 3 days ago by
GenoMax
150k
•
written 3 days ago by
Placeholder@12654926
•
0
0
votes
1
reply
216
views
1
vote
1
reply
225
views
3
votes
2
replies
269
views
0
votes
0
replies
163
views
updated 4 days ago by
GenoMax
150k
•
written 4 days ago by
laurasachica7
•
0
0
votes
4
replies
3.2k
views
updated 4 days ago by
Ram
45k
•
written 8.3 years ago by
roz_safavi
•
0
3
votes
6
replies
414
views
1
vote
0
replies
247
views
updated 4 days ago by
GenoMax
150k
•
written 4 days ago by
ilaria.palmisano
▴
10
3
votes
4
replies
328
views
1
vote
4
replies
405
views
4 days ago by
Basti
★
2.0k
0
votes
1
reply
226
views
0
votes
5
replies
445
views
0
votes
0
replies
178
views
0
votes
0
replies
215
views
updated 3 days ago by
Ram
45k
•
written 5 days ago by
Genomancer
•
0
2
votes
3
replies
318
views
0
votes
8
replies
3.0k
views
6 follow
1
vote
2
replies
588
views
1
vote
6
replies
461
views
updated 3 days ago by
andres.firrincieli
3.9k
•
written 5 days ago by
shevch2009
•
0
0
votes
2
replies
287
views
0
votes
5
replies
395
views
updated 4 days ago by
Michael
55k
•
written 5 days ago by
frarodmar17
•
0
2
votes
5
replies
398
views
updated 3 days ago by
jared.andrews07
★
18k
•
written 5 days ago by
carolofharvest
▴
50
0
votes
1
reply
382
views
updated 5 days ago by
Elisabeth Gasteiger
★
2.4k
•
written 9 days ago by
timothy.kirkwood
▴
140
4
votes
6
replies
420
views
1
vote
2
replies
427
views
15
votes
12
replies
814
views
7 follow
Forum:
Reproducibility Crisis
6
votes
13
replies
7.5k
views
7 follow
0
votes
3
replies
317
views
Recent Votes
Recent Locations •
All
Hong Kong, 2 minutes ago
Vietnam, 42 minutes ago
Iran, 45 minutes ago
United States, 56 minutes ago
United States, 1 hour ago
United States, 1 hour ago
Mexico, 1 hour ago
Recent Awards •
All
Popular Question to
dwpeng
▴
120
Popular Question to
henry slade
▴
80
Popular Question to
gernophil
▴
120
Popular Question to
Mohita
▴
50
Popular Question to
Yongjie Zhang
▴
110
Popular Question to
Sony
▴
20
Popular Question to
priyankap079
•
0
Recent Replies
Comment: Depth in Cram file does not match depth in VCF file
by
karl.stamm
4.1k
Who made the VCF file? samtools also will downsample during genotype calling. In this case, I see it reports allele depths of 4 and 2, and…
Comment: Depth in Cram file does not match depth in VCF file
by
shu8
•
0
Hi,
Thank you for answering, and I have tried to follow your instruction to turn the downsampling off in preference, but they are still d…
Comment: Depth in Cram file does not match depth in VCF file
by
GenoMax
150k
Guess you forgot to attach the image. You can edit the post above and add that.
IGV may down sample data when displaying it so make sure y…
Answer: Should I process two complete sets of 10x single-cell multiomics sequencing file
by
GenoMax
150k
Files included in this link are technical replicates from lanes 1 through 4 and have the same `S21` number: https://www.encodeproject.org/e…
Comment: Should I process two complete sets of 10x single-cell multiomics sequencing file
by
Wu-Sheng Zhang
•
0
Hi @genomax , thank you very much! So, if this is just technical replicates, does it mean I can reasoablely "merge" S7 and S31 and them pro…
Comment: Should I process two complete sets of 10x single-cell multiomics sequencing file
by
GenoMax
150k
It is a little confusing since the same sample can't be included in two rows when demultiplexing the data using `bcl-convert` (which leads …
Comment: How to filter Hmmsearch alignment
by
Mensur Dlakic
★
29k
I don't know how to help with your main question, as this is an unusual approach. You will probably have to write a custom script. Before y…
Comment: Perform DEGs with pyDESeq2 in CCLE Melanoma Data But Contains Negative Values
by
mete.han.celebi
•
0
Thank you so much for your reply! I will check it now!
Answer: Perform DEGs with pyDESeq2 in CCLE Melanoma Data But Contains Negative Values
by
ATpoint
87k
> negative values for some genes in this CCLE melanoma data. I think it arises since CCLE data is a log2 transformed
Nobody can tell you…
Comment: How to concatenate different domains in the target database identified by hmmsea
by
GenoMax
150k
See the answer here as an option -->https://www.biostars.org/p/446822/
Answer: Defining residues as buried or exposed based in ASAs/RSAs
by
Dan A
•
0
I was also interested in this topic recently. What I've tried to do is to fit a 2 component Gaussian mixture model to an array of SASA valu…
Answer: Understanding Re-use of Query Sequences in Long Read Alignments
by
LauferVA
4.6k
@charles , You're right to wonder - even a very thoughtful approach, like yours, will generate some confusion. I'll indicate some "clues" …
Comment: Associating VDJ clonotyping data with scRNA-seq in Seurat
by
garcesj
▴
50
It's a great workaround. My only question is about just removing the duplicates (`tcr <- tcr[!duplicated(tcr$barcode), ]`). Aren't we losin…
Comment: Discrepancy between BAM and vcf
by
Istvan Albert
102k
I will also say that if you take any variant caller and then look at the corresponding BAM file, you'll find many minor inconsistencies - i…
Comment: Lift over of GWAS summary stat file from Hg38 to Hg19
by
Mllepnos
•
0
Thanks a lot for the recommendation to use bcftools +munge and +liftover instead of UCSC liftOver — I’ll definitely try that!
Traffic: 1531 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6