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0
votes
4
replies
3.0k
views
Question about CREST
sequencing sequence software-error
updated 2.9 years ago by 44k • written 10.2 years ago by ▴ 810
0
votes
1
reply
9.5k
views
Comment: C: How to check the bam file of read quality with graphically visual?
updated 5.1 years ago by 44k • written 10.0 years ago by ▴ 810
1
vote
0
replies
28k
views
Comment: C: Human dna reference file with no prefix 'chr'
updated 5.1 years ago by 44k • written 10.0 years ago by ▴ 810
55
votes
11
replies
28k
views
8 follow
Human dna reference file with no prefix 'chr'
next-gen-sequencing
updated 2.5 years ago by 6.1k • written 10.0 years ago by ▴ 810
2
votes
1
reply
2.0k
views
Is there any summarized information about CANCER-related REGIONS?
gene next-gen-sequencing
updated 2.4 years ago by 44k • written 9.7 years ago by ▴ 810
11
votes
6
replies
9.5k
views
How to check the bam file of read quality with graphically visual?
next-gen genome sequence
updated 6.2 years ago by 20 • written 10.0 years ago by ▴ 810
2
votes
2
replies
4.1k
views
Can I ignore somatic mutations that are also in dbSNP when analyzing cancer-related variants?
next-gen genome sequence
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
9
votes
12
replies
7.6k
views
6 follow
Role of amino-acid change number
genome sequencing alignment
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
8
votes
7
replies
3.6k
views
Does read-depth refer to a fold?
next-gen sequencing genome
updated 2.8 years ago by 44k • written 10.1 years ago by ▴ 810
3
votes
2
replies
4.3k
views
A simple question regarding homozygous and heterozygous variation.
sequence alignment next-gen
updated 2.9 years ago by 44k • written 10.2 years ago by ▴ 810
2
votes
3
replies
2.0k
views
Excavator - Error in JointSegIn
excavator cnv
updated 2.7 years ago by 44k • written 10.0 years ago by ▴ 810
6
votes
2
replies
3.8k
views
What is the real meaning of homozygous in the tumor but heterozygous in normal samples?
genome sequencing next-gen
updated 2.9 years ago by 44k • written 10.2 years ago by ▴ 810
0
votes
3
replies
2.3k
views
genes in RAS/MEK pathway
sequencing genome
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
6
votes
5
replies
7.0k
views
I didn't understand a term about non-template DNA sequence
genome sequence next-gen
updated 2.9 years ago by 44k • written 10.2 years ago by ▴ 810
6
votes
3
replies
3.1k
views
Difference between somatic mutations and somatic hyper mutation
sequencing
updated 8.6 years ago by 7.3k • written 8.6 years ago by ▴ 810
2
votes
1
reply
1.4k
views
Terminologies about hyper mutation
sequencing
updated 8.6 years ago by 7.3k • written 8.6 years ago by ▴ 810
4
votes
1
reply
2.9k
views
Questions about CpG concept
sequencing
updated 8.6 years ago by ★ 1.1k • written 8.6 years ago by ▴ 810
0
votes
2
replies
5.4k
views
How to calculate read depth and coverage for whole exome sequencing?
next-gen alignment
updated 2.3 years ago by 44k • written 8.9 years ago by ▴ 810
23
votes
7
replies
27k
views
7 follow
What is SIFT-score?
sequencing alignment next-gen
updated 2.7 years ago by 44k • written 10.0 years ago by ▴ 810
7
votes
3
replies
2.3k
views
What is your preferred annotation techniques when you analyze mutation in exome seq?
sequencing genome sequence
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
0
votes
0
replies
3.0k
views
genomic characteristics between copy number gain and loss
sequencing genome
updated 2.2 years ago by 44k • written 9.1 years ago by ▴ 810
1
vote
1
reply
1.5k
views
Question about FIELD information in samtools
sequence next-gen-sequencing
updated 2.2 years ago by 44k • written 9.1 years ago by ▴ 810
2
votes
1
reply
1.9k
views
Question about sequence order using a software tool
sequencing alignment next-gen
updated 2.9 years ago by 44k • written 10.3 years ago by ▴ 810
2
votes
2
replies
3.7k
views
Is there any suitable annotation tool for structural rearrangements?
next-gen alignment sequence
updated 2.8 years ago by 44k • written 10.1 years ago by ▴ 810
0
votes
0
replies
2.2k
views
Comment: C: Question about mutation spectrum
9.2 years ago by mangfu100 ▴ 810
0
votes
2
replies
2.2k
views
Question about mutation spectrum
genome next-gen-sequencing
updated 2.2 years ago by 44k • written 9.2 years ago by ▴ 810
1
vote
1
reply
2.2k
views
how to normalize chromosome arms?
next-gen-sequence
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
56
votes
4
replies
72k
views
What is difference between soft-clipped and hard-clipped in SAM specification?
sequence next-gen-sequencing
updated 2.1 years ago by 44k • written 10.0 years ago by ▴ 810
0
votes
0
replies
9.4k
views
Comment: C: how to make this plot for mutation?
9.3 years ago by mangfu100 ▴ 810
9
votes
5
replies
9.4k
views
how to make this plot for mutation?
sequencing genome
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
0
votes
3
replies
7.6k
views
Comment: Comment: Role of amino-acid change number
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
0
votes
1
reply
1.7k
views
Comment: Comment: comparing amino acid change is useful when analyzing mutations?
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
0
votes
3
replies
1.7k
views
comparing amino acid change is useful when analyzing mutations?
alignment sequencing genome
updated 2.1 years ago by 44k • written 9.3 years ago by ▴ 810
0
votes
0
replies
1.8k
views
question about a term regarding copy number aberrations and genes involved in these areas.
genome next-gen-sequencing
updated 2.0 years ago by 44k • written 9.3 years ago by ▴ 810
24
votes
2
replies
20k
views
Ti Tv ratio and their usefulness in exome sequencing
genome next-gen-sequencing
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
5
votes
6
replies
2.5k
views
impact of recurrent SNVs?
next-gen alignment
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
0
votes
0
replies
5.3k
views
Comment: C: How to get mutation frequency from exome sequencing data?
9.4 years ago by mangfu100 ▴ 810
0
votes
1
reply
5.3k
views
Comment: Comment: How to get mutation frequency from exome sequencing data?
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
0
votes
1
reply
5.3k
views
Comment: Comment: How to get mutation frequency from exome sequencing data?
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
5
votes
6
replies
5.3k
views
How to get mutation frequency from exome sequencing data?
sequencing sequence
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
0
votes
1
reply
2.5k
views
Comment: Comment: impact of recurrent SNVs?
updated 23 months ago by 44k • written 9.4 years ago by ▴ 810
12
votes
14
replies
8.7k
views
6 follow
Curious about gene fusion in exome seuquencing data.
sequence next-gen
updated 2.9 years ago by 44k • written 10.2 years ago by ▴ 810
0
votes
0
replies
2.2k
views
Transcription factor binding site in Annovar
genome next-gen-sequencing
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
1
vote
1
reply
3.4k
views
Nonsynonymous Vs. non-nonysnonymous
alignment sequencing sequence
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
0
votes
0
replies
2.9k
views
questions regarding Oncotator and Annovar
sequence next-gen-sequencing
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
5
votes
5
replies
3.6k
views
Questions regarding proprocess for raw data and usage of FastQC
sequence next-gen-sequencing
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
0
votes
0
replies
2.3k
views
Comment: C: What is your preferred annotation techniques when you analyze mutation in exome
9.5 years ago by mangfu100 ▴ 810
0
votes
0
replies
1.8k
views
Comment: Comment: Can I ignore somatic mutations that are NOT located in the conserved genomic reg
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
0
votes
1
reply
1.8k
views
Comment: Comment: Can I ignore somatic mutations that are NOT located in the conserved genomic reg
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
3
votes
4
replies
1.8k
views
Can I ignore somatic mutations that are NOT located in the conserved genomic regions?
genome sequence
updated 22 months ago by 44k • written 9.5 years ago by ▴ 810
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