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459 results • Page 1 of 10
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5
votes
4
replies
368
views
Forum: Ideal PC configurations and operating system for bioinformatics laboratory
PC
2 days ago by Estevão • 0
0
votes
0
replies
178
views
Forum: Improvement on automatic annotation of single-cell RNA-seq data from the literature using LLM
annotation scRNA llm
11 days ago by yxwucq • 0
4
votes
2
replies
322
views
Forum: Bioinformatics: Where do I start
Sequencing
updated 18 days ago by 43k • written 18 days ago by ▴ 10
7
votes
7
replies
1.5k
views
Forum: Bioinformatician who was retaliated against after reporting discriminatory harassment - Please help me navigate getting out of the situation I'm in
Career advice
updated 19 days ago by ★ 2.5k • written 20 days ago by • 0
1
vote
2
replies
365
views
Forum: VCF bulk handling
bcftools SnpEff WGS VEP VCF
17 days ago by Javier • 0
16
votes
10
replies
1.1k
views
6 follow
Forum: F*up Night style events for Bioinformatics ? Comment if you're interested!
mistakes
updated 5 weeks ago by 5.3k • written 5 weeks ago by ★ 2.4k
1
vote
1
reply
230
views
Forum: Can I use this community for software development?
software-development
updated 5 weeks ago by 43k • written 5 weeks ago by • 0
5
votes
2
replies
395
views
Forum: Can questions and answers on biostars be asked only in English? Can't I use Russian for example?
language
updated 5 weeks ago by 54k • written 5 weeks ago by • 0
0
votes
0
replies
180
views
Forum: Field of Study in Computational Biology
Genomics Computational-Biology PhD
updated 6 weeks ago by 43k • written 6 weeks ago by • 0
1
vote
3
replies
488
views
Forum: Development plan for a bioinformatics database developer/coder
developer
7 weeks ago by pixie@bioinfo ★ 1.5k
7
votes
8
replies
722
views
Forum: Bioinformatics career transition
career forum
updated 7 weeks ago by ★ 16k • written 7 weeks ago by ▴ 20
4
votes
2
replies
498
views
Forum: Exploring Amino Acid Patterns in Proteins Through N-gram Analysis
protein CAFA5
8 weeks ago by Anatoly A. ▴ 10
6
votes
6
replies
788
views
Forum: You have 3 days of zero obligations and expansive resources. What are you building?
hypothetical thought-experiment
8 weeks ago by jared.andrews07 ★ 16k
0
votes
0
replies
170
views
Forum: What other data types and pipelines you would like to see from the Genomics Data Commons (GDC)
gdc tcga genomics-data-commons
updated 8 weeks ago by 43k • written 8 weeks ago by ★ 1.2k
0
votes
2
replies
397
views
Forum: What's the state of the art in bacterial whole genome alignment?
whole genome alignment mauve
8 weeks ago by Dave Carlson ★ 1.7k
31
votes
12
replies
1.0k
views
7 follow
Forum: Nextflow and self-made pipelines opinion
nextflow pipeline data-analysis
9 weeks ago by karlaarz ▴ 90
5
votes
4
replies
575
views
Forum: Would reaching out to local labs and startups help with my career transition?
career volunteering
updated 10 weeks ago by 142k • written 10 weeks ago by ▴ 10
1
vote
2
replies
381
views
Forum: Exploring Career Reentry: Challenges and opportunities for Women After Maternity and Childcare Breaks
Maternity Career-Gap career-reentry
updated 10 weeks ago by 82k • written 10 weeks ago by ▴ 20
8
votes
7
replies
826
views
6 follow
Forum: Tower Server configuration for NGS data analysis
NGS
updated 10 weeks ago by ▴ 120 • written 3 months ago by • 0
1
vote
0
replies
287
views
Forum: list of bioinformatics tools in cancer genomics
mutations CNA cancer genomics LOH
updated 11 weeks ago by 161k • written 11 weeks ago by ★ 1.4k
4
votes
2
replies
388
views
Forum: bulk seq vs. sc-seq
scATAC-seq ATAC-seq scRNAseq RNAseq
updated 12 weeks ago by ★ 6.0k • written 12 weeks ago by ▴ 10
8
votes
6
replies
2.8k
views
Forum: Demonstrating Exponential Growth In Pre-School
education
written 10.2 years ago by 10k
0
votes
0
replies
210
views
Forum: tutorial for carrier screening analyses?
carrier-screening
updated 3 months ago by 43k • written 3 months ago by ▴ 20
2
votes
3
replies
445
views
Forum: My Project
Project CLI MD-Simulations Molecular-docking
3 months ago by Ajay A Shettigar • 0
17
votes
11
replies
1.0k
views
Forum: How to overcome the imposter syndrome in bioinformatics?
advice
3 months ago by sil_bioinfo ▴ 40
10
votes
7
replies
2.2k
views
Forum: How to learn bioinformatics?
learning
updated 3 months ago by ★ 1.3k • written 23 months ago by ▴ 20
26
votes
27
replies
2.1k
views
10 follow
Forum: Determining computer time required
computer hpc time
updated 3 months ago by ★ 6.0k • written 3 months ago by ▴ 40
7
votes
6
replies
745
views
Forum: where to work as a bioinformatician (NGS/IA)
employment omics ia ngs
updated 3 months ago by 43k • written 3 months ago by ▴ 20
21
votes
12
replies
3.6k
views
Forum: How to Use Biostars Part-3: Formatting Text and Using GitHub Gists
meta how-to documentation
3 months ago by Ram 43k
2
votes
1
reply
440
views
Forum: Cataloguing available spatial transcriptomics tools, then linking them together into a workflow?
cytassist transcriptomics nanostring xenium visium
3 months ago by LauferVA 4.2k
49
votes
20
replies
2.1k
views
10 follow
Forum: First experiences matter
first-time tolerance
updated 3 months ago by ★ 2.6k • written 4 months ago by ★ 27k
4
votes
3
replies
786
views
Forum: How to get started in bioinformatics
students
updated 3 months ago by 43k • written 4 months ago by ▴ 10
2
votes
2
replies
590
views
Forum: Do batches contain biological variations in omics data (RNAseq or scRNAseq)?
combat single-cell omics batch rnaseq
updated 4 months ago by 43k • written 4 months ago by ▴ 40
0
votes
2
replies
3.2k
views
Forum: I’m considering a career transition from software engineering to bioinformatics. Is it a good fit for me?
career
updated 4 months ago by 142k • written 4 months ago by ▴ 10
5
votes
3
replies
620
views
Forum: Binning the rare biosphere
metagenomics soil assembly techniques binning
updated 4 months ago by ★ 27k • written 4 months ago by ▴ 20
6
votes
2
replies
674
views
Forum: how to start Bioinformatics?
basics
updated 4 months ago by ★ 27k • written 4 months ago by • 0
19
votes
5
replies
1.1k
views
6 follow
Forum: What Are The Most Influential Bioinformatics/Computational Biology Papers Of 2023?
genomics snps survey papers
4 months ago by Raony Guimarães ★ 1.4k
4
votes
6
replies
938
views
6 follow
Forum: Bioinformatics: what do you think of it in the next 20 years?
future
updated 5 months ago by 43k • written 5 months ago by • 0
1
vote
1
reply
497
views
Forum: want to work in open source project/project in bioinformatics
project
updated 5 months ago by 43k • written 5 months ago by • 0
3
votes
5
replies
1.0k
views
Forum: Current Trends in Bioinformatics
structural-bioinformatics
updated 5 months ago by 43k • written 5 months ago by • 0
21
votes
11
replies
2.5k
views
6 follow
Forum: Rust bioinformatics projects ideas
projects scRNA-seq RNA-seq Rust
updated 5 months ago by 22k • written 14 months ago by ▴ 150
176
votes
46
replies
19k
views
26 follow
Forum: Crac: Funny And/Or Weird Names For Bioinformatics Tools
humor
5 months ago by Istvan Albert 100k
3
votes
2
replies
629
views
Forum: RNA-Seq data analysis - question
Python RNA-Seq R
updated 5 months ago by ▴ 10 • written 5 months ago by ▴ 40
0
votes
0
replies
377
views
Forum: How to learn bioinformatics online?
self-education education learning
updated 6 months ago by 43k • written 6 months ago by • 0
6
votes
5
replies
2.3k
views
Forum: Maintaning internal or private installation of Biostar or a similar Q&A site
Biostars
6 months ago by tshtatland ▴ 190
7
votes
9
replies
1.4k
views
6 follow
Forum: Mentor for a beginner bioinformatics student
project mentor
6 months ago by UT_FAN ▴ 40
0
votes
0
replies
466
views
Forum: Steps after doublet detection in single cell data
scRNA doublet
6 months ago by ishwarvh • 0
0
votes
0
replies
361
views
Forum: Automated Checks And QA
retrospective
6 months ago by Sasha ▴ 840
7
votes
13
replies
1.4k
views
Forum: How do you validate and verify your pipeline's software updates?
Validation Verification Quality-Assurance
updated 6 months ago by 43k • written 7 months ago by ▴ 10
21
votes
7
replies
11k
views
Forum: Bioinformatics short paper journal resource [software/webapps/database]
journal software webapp
updated 7 months ago by ▴ 100 • written 8.1 years ago by 11k
459 results • Page 1 of 10
Recent Votes
Comment: GRCh38.gmap file
Answer: GRCh38.gmap file
Answer: GRCh38.gmap file
Answer: Design matrix Differential expression analysis
A: PCA plot from read count matrix from RNA-Seq
A: PCA plot from read count matrix from RNA-Seq
Answer: Design matrix Differential expression analysis
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Recent Awards • All
Popular Question to psm ▴ 130
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Recent Replies
Comment: Design matrix Differential expression analysis by Gordon Smyth ★ 7.1k
> When is it recommended to use the design <- cbind(Intercept=1,Group=c(-1,-1,-1,1,1,1)) It is not recommended. No such code appears anywh…
Comment: GRCh38.gmap file by lorena9132 ▴ 10
Hi Mathew, The .txt files provided in the link differ from the .gmap files, but after several attempts, I succeeded in generating the .gma…
Answer: GRCh38.gmap file by Mathew ▴ 20
Hi, I have spent some time searching for a GRCH38 map file for you. I have found a certain publication that uses a hg38 genetic map file…
Answer: Association study using SNP data by Mathew ▴ 20
Hi, You asked three questions so I will attempt to help the best I can **What should be the optimal GC score cutoff** It sounds li…
Comment: Design matrix Differential expression analysis by SHN ▴ 40
Thank you for your explanation. I am working on the cell lines and I am investigating the effect of the treatment on the expression level, …
Answer: Issues with Mixture file when using CIBERSORTx by vjanve • 0
I ran into same issue of "duplicated gene symbol(s)": 1: In CIBERSORTxFractions(sigmatrix = sigmatrix, mixture = mixture, : 22292 dup…
Comment: creating batch colum for batch correction by Expert ▴ 10
Thank you for your response. These samples were collected from the same patient at different time points(day 0, 8 and 18) and these are ind…
Comment: creating batch colum for batch correction by ATpoint 82k
Not sure I follow. Can you first of all describe which comparisons you want to make, pretending there was no batch effect at all. Write dow…
Comment: Pindel Segmentation Fault Error by Ruqaiya • 0
This the tool still problematic?
Comment: Segmentation error while using a tool by Ruqaiya • 0
Thank you for the advice, i'll keep that in mind.
Comment: Segmentation error while using a tool by Ruqaiya • 0
I am trying to reproduce some bioinformatics data from a research paper-[this paper][1] as i was asked to work on an MRSA bioinfo project, …
Answer: Segmentation error while using a tool by Mensur Dlakic ★ 27k
Most likely you didn't do anything wrong. Going by your previous post that you have only 8 GB of RAM, the most likely reason is the lack of…
Comment: Segmentation error while using a tool by Thanujay S • 0
Hey @Ruqaiya! Can you please give more details on why smalt is opted here? According to what I can see, the tool has become obsolete! Why …
Comment: Extracting mutation status from MAF files - TCGA by Thanujay S • 0
Hey! Can you explain the question further? What have you tried?
Comment: Downloading older version of a tool by Ruqaiya • 0
I tried the 2nd option only. I got the files of older version from the author but that version isn't working on my WSL, it's showing Segmen…
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